Milly Mathew started her career in teaching in Sri Ramachandra Medical College & Research Institute, Chennai. She was Professor of Medicine in Pondicherry Institute of Medical Sciences. She is a Fellow of the Royal College of Physicians of Glasgow and London. She has served as MRCP examiner for many terms since 2009. At present, she is working as a Senior Consultant in MGM Healthcare, Chennai. She has many medical publications in many national and international journals.